Letter from Dr. M. Mayer of Charleston, South Carolina, to Reverend Isaac Leeser in Philadelphia, Pennsylvania, dated October 5, 1857. The letter is a detailed response to a previous letter from Leeser, primarily addressing the establishment of a new Sephardim congregation in Philadelphia. Mayer expresses his opinion that the creation of the new congregation was unjustified, lacking a basis in doctrinal differences, and characterizing the secession as "rebellion." He discusses the arguments for and against the new congregation, referring to articles in the Asmonean and other publications. The letter also touches upon the role and effectiveness of Jewish Sunday schools. A postscript, dated November 25, 1857, adds further comments and observations.